|
|
5''-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole <=> fumarate + 5-aminoimidazole-4-carboxamide_ribonucleotide
|
4.3.2.2
adenylosuccinate lyase
|
–
|
BMK
|
| |
BRENDA:
BR12741
KEGG:
R04559
MetaCyc:
AICARSYN-RXN
SABIO-RK:
121
|
|
|
|
5-aminoimidazole-4-carboxamide_ribonucleotide + formate + ATP <=> 5-Formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide + ADP + phosphate
|
6.3.4.23
formate---phosphoribosylaminoimidazolecarboxamide ligase
|
–
|
BMK
|
| |
BRENDA:
BR50732
KEGG:
R06975
MetaCyc:
RXN-10066
|
|
|
|
phosphoribulosylformimino-AICAR-phosphate + L-glutamine <=> H+ + L-glutamate + D-erythro-1-(imidazol-4-yl)glycerol_3-phosphate + 5-aminoimidazole-4-carboxamide_ribonucleotide
|
2.4.2
4.3.1.B2
4.3.2.10
imidazole glycerol-phosphate synthase
|
–
–
–
|
BMK
|
| |
BRENDA:
BR51141;
BR52465
KEGG:
R04558
MetaCyc:
GLUTAMIDOTRANS-RXN
SABIO-RK:
4234
|
|
|
|
phosphoribulosylformimino-AICAR-phosphate + NH3 <=> D-erythro-1-(imidazol-4-yl)glycerol_3-phosphate + 5-aminoimidazole-4-carboxamide_ribonucleotide + H2O + H+
|
4.3.1.B2
4.3.2.10
imidazole glycerol-phosphate synthase
|
–
–
|
|
| |
BRENDA:
BR51142;
BR52466
KEGG:
R12152
MetaCyc:
RXN-17900
SABIO-RK:
7138
|
|
|
|
5-aminoimidazole-4-carboxamide_ribonucleotide + diphosphate <=> 5-aminoimidazole-4-carboxamide + 5-phospho-alpha-D-ribose_1-diphosphate
|
2.4.2.7
adenine phosphoribosyltransferase
|
–
|
K
|
| |
BRENDA:
BS355041
KEGG:
R04378
MetaCyc:
RXN-14270
|
|
|
|
10-formyltetrahydrofolate + 5-aminoimidazole-4-carboxamide_ribonucleotide <=> tetrahydrofolate + 5-Formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide
|
2.1.2.3
phosphoribosylaminoimidazolecarboxamide formyltransferase
|
–
|
BMK
|
| |
BRENDA:
BR43942
KEGG:
R04560
MetaCyc:
AICARTRANSFORM-RXN
SABIO-RK:
122
|
|
|
|
10-formyltetrahydrofolate + 5-aminoimidazole-4-carboxamide_ribonucleotide <=> tetrahydrofolate + 5-formamido-4-imidazole_carboxamide_ribonucleotide
|
2.1.2.3
phosphoribosylaminoimidazolecarboxamide formyltransferase
|
–
|
|
| |
BRENDA:
BS320058
|
|
|
|
N10-formyltetrahydropteroylglutamate + 5-aminoimidazole-4-carboxamide_ribonucleotide <=> 7,8-dihydrofolate + 5-Formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide
|
2.1.2.3
phosphoribosylaminoimidazolecarboxamide formyltransferase
|
–
|
|
| |
BRENDA:
BS419230
|
|
|
|
N10-formyltetrahydropteroylglutamate + 5-aminoimidazole-4-carboxamide_ribonucleotide <=> tetrahydrofolate + 5-formamido-4-imidazole_carboxamide_ribonucleotide
|
2.1.2.3
phosphoribosylaminoimidazolecarboxamide formyltransferase
|
–
|
|
| |
BRENDA:
BS320057
|
|
|
|
IMP + beta-glycinamide_ribonucleotide + H2O <=> 5-aminoimidazole-4-carboxamide_ribonucleotide + formylglycinamide_ribonucleotide
|
2.1.2.2
phosphoribosylglycinamide formyltransferase
|
–
|
|
| |
BRENDA:
BS320045
|
|
|
|
5-aminoimidazole-4-carboxamide_ribonucleotide + H2O <=> 5-aminoimidazole-4-carboxamide + D-ribose
|
3.2.2.8
ribosylpyrimidine nucleosidase
|
–
|
|
| |
BRENDA:
BS94862
|
|
